Methods of reducing the bacterial resistance

Dr. Zeinali, a very experienced clinical veterinarian in the poultry industry has for many years explored effective approaches to reducing Antibiotic Growth Promoters in animal rearing and consequently reducing bacterial resistance. In this article Dr. Zeinali shares short but on-point insights on how you can also create a “Better Tomorrow” by adopting a NAGP approach.

” I have worked for more than 32 years as a clinical veterinarian and consultant with a focus on diagnosis, treatment, prevention, nutrition, management in layer breeder, broiler breeder, commercial layer, and commercial broiler farms.

According to my extensive background and experience I recommend following principles to reduce the consumption of the treatment antibiotics and eliminate the growth promotor antibiotics in the poultry industry:

1. Management: No doubt the rigid and serious management of antibiotic consumption is a necessary and important factor.

2. Biosecurity: including the biosecurity in a commercial farm, breeder farm, hatchery, feed factory, slaughterhouse that has great importance in controlling diseases and reduce the use of antibiotics.

3. Clean water: Free of chemical, physical and microbial contamination.

4. Ventilation: to provide proper oxygen, temperature, moisture and clean air with minimum physical, chemical and microbial contamination.

5. Nutrition: should be free of toxins, heavy metals, and pathogens, and provide nutrients that are needed as for racial physiological needs, breeding condition, production, regional diseases, vaccination status, chicken density etc.

6. Alternatives: Use of the alternatives while improving growth and FCR can control and reduce poultry diseases that our main discussion will be in the following article.

Antibiotics alternatives

A- Probiotics

Probiotics are live microbial food supplements that can improve microbial flora of intestine and have beneficial effects in resistance to diseases

A-1. Probiotics function

• Competitive alternative for harmful bacteria to remove them

• Intestine pH adjustment to remove harmful bacteria

• Competing with harmful bacteria in consumption of available food

• Production of Bacteriocins (specific inhibitors) to kill harmful bacteria such as E.coli, Salmonella and Staphylococcus

• Lack of Lactic acid antibacterial antibody production due to Muramyl dipeptide (MDP) in the cell wall

• Increase the body resistance against diseases:

  •     Macrophages and Lymphocytes activities increase

  •     Antibody production increase

  •     NK-cell (Natural Killer cell) increase

  •     Phagocytosis and involved enzymes increase

• Stimulation of Interferon production

  •     Interferon is produced by Fibroblasts, Lymphocytes and T-helpers

  •     Interferon prevents of protein production by cells infected by viruses

  •     Interferon stimulates the immune cells such as NK-cells and microphages

• Enteritis control

• Absorbing surface increase

• Weight gain rate increase

• FCR decrease

A-2. Characteristics and Properties of an Effective Probiotic

• Being resistant in body conditions (Enzymes, Bile and pH)

• Ability to replacement and staying in the intestine

• Keeping up its natures in the intestine

• Non-sensitive to antibiotics

• Ability to boost the immune system

• Without any toxic and allergic effects

• Positive effects on the host`s health

• Ability to be synthesized in large scale as a live product

• Long shelf life

• Reasonable resistance to heat in pellet production process

This article will continue, also I need to mention that antibiotic alternatives produced by XVET company can be helpful to reduce the consumption of antibiotics and prevent the resistance to antibiotics. “

By Dr. Ali Zeinali, Ambassador for lessantibiotics.com