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Ambassador for lessantibiotics.com NAGP approach

  • June 5, 2018August 30, 2019
First Ambassador for lessantibiotics.com NAGP approach

What is Antimicrobial resistance and how does it spread? 

Around the world, the support of a Non-Antibiotic Growth Promotion approach is growing therefore, NAGP Ambassadors will start to share their experiences and know-how to support farmers through a responsible transition. First  Ambassador for lessantibiotics.com NAGP approach is Dr. Ali Zeinali, a Poultry specialist from Iran with many years of experience, who in this article describes his understanding of antibiotic reduction explaining antimicrobial resistance.
“In the following and in subsequent articles, I will talk about antibiotic alternatives and  XVET products that have been a great way to remove the Antibiotic Growth Promotors and reduce the antibiotics for treatments.
Below is the introduction for reduction Antibiotic consumption (lessantibiotics) in the poultry industry.

The reason of bacterial resistance to antibiotics
  • Overuse antibiotics in humans and animals
  • Inappropriate prescribing
  • Irregular and long-term use
  • Residual antibiotics
  • Use of promotor antibiotics in animals
  • There are no legal barriers in many countries
  • Availability of few new antibiotics
Method and development of bacterial resistance to antibiotics
  • Genetic basis of anti-bacterial resistance
  • Horizontal gene transfer
  • Mutational resistance
  • Mechanistic basis of bacterial resistance that includes
    • modification of the antibiotic molecule
    • decreased antibiotic penetration and efflux
    • changes in target sites
    • resistance due to global cell adaptations

      Horizontal Gene Transfer: There are three mechanisms by which horizontal gene transfer can occur. Specifically, the exchange of plasmid DNA falls under transformation. Source: https://courses.lumenlearning.com
Examples of how the use of antibiotics in animal production creates resistance in Humans. Infographic from the CDC Threat Report 2013, Antibiotic resistance threats in the United States, 2013 (https://www.cdc.gov/drugresistance/threat-report-2013/)
As a conclusion, animal rearing should focus on alternatives to antibiotic growth promoters, that not only protect the animal and promotes their health in the meantime it also improves the growth and FCR.  Non-Antibiotic Growth Promoters also reduce harmful bacteria and increase the immune system activity which results in a decreased need for antibiotic consumption for treatment too. “
By Dr. Ali Zeinaldi – lessantibiotics.com Ambassador  

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